The Benefits of Labisia Pumila for Women: A Literature Review

Ika Yulianti

Abstract

Objective: Traditionally, Labisia Pumila plant decoction was consumed for labor induction but, there is not enough scientific evidence about its safety. although many studies have explained the benefits of labisia pumila for the life cycle of women. For this reason, understanding the possible benefits of Labisia Pumila in the scientific life cycle of women's evidence is very important. In this review, the author will discuss various studies that can explain the benefits of labisia pumila in a woman's life cycle

Method: The author searches databases including PubMed, EMBASE, and CINAHL to find out potential studies that meet the requirements. The keywords used include: ‘Labisia pumila 'OR' labisia pumila and woman abis labisia pumila and its benefits’ OR ‘kacip fatimah’ OR ‘rumput fatimah’. This search was conducted from February to March 2019.

Result: 12 articles were included and reported the benefits of Labisia Pumila reported consisting of phenolic compounds, flavonoids, saponins, alkenyl, benzoquinone, natural estrogen or phytoestrogenic. In vitro study  showed that ethanol extract from the root of L. pumila var increased the secretion of alkaline phosphatase.

Conclusion: Labisia Pumila has many phytochemical benefits such as antioxidant, antimicrobial, anti-inflammatory, and can replace ERT.

 Full Text:

PDF

References

Al-Wahabi, A.., Wan Nazaimoon, WM., Farihah, HS., and Azian, AL. (2007) ‘Effect of Ovariectomy, Labisia pumila var alata Treatment and Estrogen Replacement Therapy on the Morphology of Adipose Tissue in Ovariectomized Sprague Dawley Rats’, Journal of Medicine.

Amrah,. Suhaimi, AWM., Mohsin, SSJ., and Wan Ezumi, MF (2009) ‘Evaluation of the female reproductive toxicity of aqueous extract of Labisia pumila var. alata in rats’, Indian Journal of Pharmacology, 39(1), p. 30.

Dianita, R., Jantan, I., Jalil, J., and Amran, AZ. (2016) ‘Effects of Labisia pumila var alata extracts on the lipid profile, serum antioxidant status and abdominal aorta of high-cholesterol diet rats’, Phytomedicine. Elsevier GmbH, 23(8), pp. 810–817.

Effendy, NM., Khamis, MF. and Shuid, AN. (2017) ‘The effects of Labisia pumila extracts on bone microarchitecture of ovariectomized-induced osteoporosis rats: A micro-CT analysis’, Journal of X-Ray Science and Technology, 25(1), pp. 101–112.

Faizal, A. and Geelen, D. (2013) ‘Saponins and their role in biological processes in plants’, Phytochemistry Reviews.

Heinrich, M. (2002) ‘Handbook of Phytochemical Constituents of GRAS Herbs and other Economic Plants’, Journal of Ethnopharmacology.

Intan Idiana, H., Law, K S., Azreena, A., Norhayati, MN., Wan Z, Wan, ML., Eckehard NH., et al. (2014) ‘ Efficacy and Safety of Labisia pumila var alata Water Extract Among Pre- and Postmenopausal Women ’, Journal of Medicinal Food, 17(8), pp. 929–938.

Jamia, AJ., Houghton, PJ., Milligan, SR., and Ibrahim, J. (2003) ‘The Oestrogenic and Cytotoxic Effects of the Extracts of Labisia pumila var pumila In Vitro’, Sains Kesihatan.

Karimi, E., Jaafar, H. Z. E. and Ahmad, S. (2011) ‘Phytochemical analysis and antimicrobial activities of methanolic extracts of leaf, stem and root from different varieties of labisa pumila benth’, Molecules.

Kim, MH., Jo, SH., Ha, KS., Song, JH., Jang, HD., and Kwon, YI.. (2010) ‘Antimicrobial activities of 1,4-Benzoquinones and wheat germ extract’, Journal of Microbiology and Biotechnology.

Mannerås, L., Fazliana, M., Wan Nazaimoon, WM,. Lönn, M., Gu, HF., Östenson, CG., and Stener-Victorin, E. (2010) ‘Beneficial metabolic effects of the Malaysian herb Labisia pumila var. alata in a rat model of polycystic ovary syndrome’, Journal of Ethnopharmacology.

Mariati, N. (2016) ‘TERHADAP OSTEOKALSIN SERUM DAN DEOXYPIRIDINOLIN URIN. RAKERNAS Asosiasi Insti-tusi Pendidikan Kebidanan Muhammadiyah Aisyiyah (AIPKEMA).

Mohamad, N., Mahmood, M. and Mansor, H. (2009) ‘Antioxidative properties of leaf extracts of a popular Malaysian herb, Labisia pumila’, Journal of Medicinal Plants Research.

Nani, D. (2010) ‘Perubahan Amplitudo Kontraksi Otot Uterus Tikus Akibat Pemberian Rumput Fatimah (Anastatica hierochuntica L)’, Mandala Health, 4(1), pp. 47–52.

Norhanisah, A, . Siavash, HC., Chua, LS.and Mohammad Roji, S. (2013) ‘Labisia pumila : A Review on its Traditional , Phytochemical and Biological Uses’, World Applied Sciences Journal, 27(10), pp. 1297–1306.

Petronellia, A., Pannitterib, G. and Testaa, U. (2009) ‘Triterpenoids as new promising anticancer drugs’, Anti-Cancer Drugs.

Proestos, C. and Komaitis, M. (2006) ‘Ultrasonically assisted extraction of phenolic compounds from aromatic plants: Comparison with conventional extraction technics’, Journal of Food Quality.

Shuid, AN., Ping, LL., Muhammad, N., Mohamed, N.,and Soelaiman, IN. (2011) ‘The effects of Labisia pumila var. alata on bone markers and bone calcium in a rat model of post-menopausal osteoporosis’, Journal of Ethnopharmacology.

Wan Ezumi Mohd, F., Siti Amrah, S., Mohamad, Nl., Mohd Suhaimi AW., and Syed Mohsin Sahil, J. (2005) ‘Evaluation of the Teratogenicity of Aqueous Extract’, Malaysian Journal of Medical Sciences, 12(2), pp. 13–21.

Refbacks

  • There are currently no refbacks.